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Week 4 of the 2010 college football campaign is going to get underway this weekend. Below you will find the current list of 2010 Week 4 NCAA football lines and spreads along with a breakdown of the Week 4 college football lines. Be sure to check out the free NCAA football picks from the expert handicappers at Bankroll Sports this weekend!

The Miami Hurricanes and Pittsburgh Panthers are going to kick off the NCAA football betting weekend on Thursday night from the Steel City in a game that pits two former conference foes against each other. Both teams are 1-1 this season and both are coming off of bye weeks. Needless to say, these two squads are incredibly evenly matched, even in the Heisman Trophy race. Both Miami QB Jacory Harris and U-Pitt RB Dion Lewis are dark horse candidates as Heisman Trophy picks as well.

On Friday night, the TCU Horned Frogs could get one of their sterner tests of the season when they take on the SMU Mustangs in an instate rivalry. The other mid-major player for the National Championship, the Boise State Broncos, will open up their 2010 home slate at the Smurf Turf when they take on the Oregon State Beavers in one of Saturday’s biggest clashes.

The ACC might not have a slew of top teams this year, but there are certainly going to be some interesting matchups to keep an eye on in conference play. The Virginia Tech Hokies didn’t get off to a good start to the season, but head coach Frank Beamer might be able to get his guys ready for a run at the BCS anyway. They’ll start off against the Boston College Eagles. The only undefeated team left in the conference, the NC State Wolfpack, will travel to Atlanta to take on the Georgia Tech Yellow Jackets.

Top 25 teams are on upset alert across the country on Saturday once again. Leading the way will be the red hot Stanford Cardinal, who are up to #17 in the land and have outscored their foes by 114 points this year. However, the Notre Dame Fighting Irish could just as easily be 3-0 right now as they are 1-2 and will provide a very, very tough task. The undefeated Temple Owls just beat the Connecticut Huskies last week, and they’ll have a chance to do more damage against the Penn State Nittany Lions in Happy Valley. In the Pac-10, the two teams with arguably the best chance of going to the Rose Bowl have tough openers to deal with. The Arizona Wildcats, fresh off of their huge win over the Iowa Hawkeyes, will take on the California Golden Bears at home, while the Oregon Ducks will head to the desert to take on the Arizona State Sun Devils, who came a blocked PAT short of upsetting the Wisconsin Badgers last week.

However, there are three games that all NCAA football betting fans will be glued to this weekend, and all three involve SEC teams.

The LSU Tigers gave up 21 points in the fourth quarter to the North Carolina Tar Heels in Week 1, but if you take that quarter out, they have only conceded 13 for the rest of the season. They’ll have their biggest test of the year against the West Virginia Mountaineers in the late night start in Baton Rouge. Heading into the sea of purple and gold could be devastating for a young quarterback, and QB Geno Smith is about to find out just how tough Cajun Country can be.

In the primetime game of the night, the Auburn Tigers and South Carolina Gamecocks will do battle. War Eagle just barely survived last week against the Clemson Tigers in overtime, while South Carolina is going to be facing its first road test. This will be a great matchup between South Carolina’s stout rush defense, which ranks sixth in the country, and Auburn’s amazing trio of rushers, RB Onterio McCalebb, RB Michael Dyer, and QB Cam Newton.

However, in the main course and what might be one of the best games of the entire season, the Arkansas Razorbacks will face the Alabama Crimson Tide. The Tide have been rolling this year, and with a health RB Mark Ingram in the fold, they’re clearly at full strength. Arkansas escaped by upsetting the NCAA football odds last week “Between the Hedges,” and in the process, QB Ryan Mallett might have made himself the Heisman Trophy betting lines favorite. The winner will have a clear inside track to the SEC West title. Alabama has to be careful not to be looking forward to that battle next week at home against the Florida Gators, as this game could be just as difficult, if not harder than that one will be.

2010 NCAA Football Week 4 Odds @ BetUS Sportsbook (as of 9/24/10):
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Week 4 Lines for Thursday, 9/23/10

301 Miami Hurricanes -4
302 Pittsburgh Panthers +4
Over/Under 50.5

Week 4 Spreads for Friday, 9/24/10

303 TCU Horned Frogs -18
304 SMU Mustangs +18
Over/Under 51

Week 4 Odds for Saturday, 9/25/10

305 Central Michigan Chippewas +6.5
306 Northwestern Wildcats -6.5
Over/Under 51

307 Toledo Rockets +11.5
308 Purdue Boilermakers -11.5
Over/Under 50

309 Bowling Green Falcons +25.5
310 Michigan Wolverines -25.5
Over/Under 57.5

311 Ball State Cardinals +28
312 Iowa Hawkeyes -28
Over/Under 46

313 Eastern Michigan Eagles +44
314 Ohio State Buckeyes -44
Over/Under 57

315 Virginia Tech Hokies -4
316 Boston College Eagles +4
Over/Under 47

317 Temple Owls +14
318 Penn State Nittany Lions -14
Over/Under 43.5

319 NC State Wolfpack +8
320 Georgia Tech Yellow Jackets -8
Over/Under 57.5

321 Wake Forest Demon Deacons +20
322 Florida State Seminoles -20
Over/Under 62.5

323 Army Black Knights +6.5
324 Duke Blue Devils -6.5
Over/Under 55.5

325 Buffalo Bulls +20
326 Connecticut Huskies -20
Over/Under 48.5

327 Georgia Bulldogs pk
328 Mississippi State Bulldogs pk
Over/Under 46.5

329 Fresno State Bulldogs +2
330 Mississippi Rebels -2
Over/Under 52.5

331 Miami Redhawks +20
332 Missouri Tigers -20
Over/Under 51.5

333 Air Force Falcons -13.5
334 Wyoming Cowboys +13.5
Over/Under 50

335 UCF Knights +7
336 Kansas State Wildcats -7
Over/Under 45.5

337 Tulane Green Wave +19
338 Houston Cougars -19
Over/Under 56.5

339 Oklahoma Sooners -14
340 Cincinnati Bearcats +14
Over/Under 52

341 Alabama Crimson Tide -7
342 Arkansas Razorbacks +7
Over/Under 56

343 Oregon State Beavers +18
344 Boise State Broncos -18
Over/Under 56

345 Stanford Cardinal -4.5
346 Notre Dame Fighting Irish +4.5
Over/Under 59.5

347 California Golden Bears +6.5
348 Arizona Wildcats -6.5
Over/Under 56.5

349 UCLA Bruins +15.5
350 Texas Longhorns -15.5
Over/Under 43

351 Idaho Vandals -8
352 Colorado State Rams +8
Over/Under 50.5

353 Nevada Wolfpack -4
354 BYU Cougars +4
Over/Under 63

355 USC Trojans -22
356 Washington State Cougars +22
Over/Under 55.5

357 New Mexico State Aggies +23
358 Kansas Jayhawks -23
Over/Under 51

359 Kentucky Wildcats +14
360 Florida Gators -14
Over/Under 49

361 Southern Mississippi Golden Eagles -3.5
362 Louisiana Tech Bulldogs +3.5
Over/Under 55.5

363 UAB Blazers +14
364 Tennessee Volunteers -14
Over/Under 51

365 Akron Zips +22.5
366 Indiana Hoosiers -22.5
Over/Under 57.5

367 Ohio Bobcats +6.5
368 Marshall Thundering Herd -6.5
Over/Under 46

369 South Carolina Gamecocks +3
370 Auburn Tigers -3
Over/Under 46

371 San Jose State Spartans +30.5
372 Utah Utes -30.5
Over/Under 52

373 Utah State Aggies +8.5
374 San Diego State Aztecs -8.5
Over/Under 61.5

375 West Virginia Mountaineers +10
376 LSU Tigers -10
Over/Under 43.5

377 Baylor Bears -7.5
378 Rice Owls +7.5
Over/Under 56.5

379 North Carolina Tar Heels -3
380 Rutgers Scarlet Knights +3
Over/Under 44.5

381 Northern Illinois Huskies +4
382 Minnesota Golden Gophers -4
Over/Under 49.5

383 Memphis Tigers +11.5
384 UTEP Miners -11.5
Over/Under 59.5

385 New Mexico Lobos +10.5
386 UNLV Rebels -10.5
Over/Under 50

387 Oregon Ducks -11.5
388 Arizona State Sun Devils +11.5
Over/Under 57

389 Arkansas State Red Wolves +10.5
390 Troy Trojans -10.5
Over/Under 67

391 Middle Tennessee State Blue Raiders -2
392 Louisiana Lafayette Ragin’ Cajuns +2
Over/Under 50.5

393 North Texas Mean Green +10
394 Florida Atlantic Owls -10
Over/Under 50

395 Western Kentucky Hilltoppers +28.5
396 South Florida Bulls -28.5
Over/Under 58

397 Florida International Golden Panthers +12
398 Maryland Terrapins -12
Over/Under 44.5