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Week 2 of the 2010 NFL campaign is going to get underway this weekend. Below you will find the current list of 2010 week 2 NFL lines and spreads along with a breakdown of the week 2 NFL lines. Be sure to check out the free NFL picks from the expert handicappers at Bankroll Sports this weekend…..  

The Manning brothers are going to be highlighting what should be another fantastic week of NFL football wagering action. The New York Giants will send younger brother Eli up against the Indianapolis Colts and older brother Peyton. These teams started off the year in two vastly different directions, as the Colts were run over by the Houston Texans 34-24, while the Giants were busy making mincemeat out the Carolina Panthers 31-18. The current week two lines at Oddsmaker currently have the Colts listed at 5.5 point favorites in their home opener at Lucas Oil Stadium.

The biggest favorites of all the 2010 week two NFL spreads at this point are the Green Bay Packers. The Pack are coming off of an impressive seven point road win at the Philadelphia Eagles on Sunday, and they are coming home for the first time to take on the Buffalo Bills, who were scorched by the Miami Dolphins 15-10. Green Bay is listed at a big 13 point favorite.

Whereas Week 1 featured a ton of home underdogs, the second week of the regular season only features three hosts that are pups. On Monday Night Football, the San Francisco 49ers will try to rebound from their embarrassing defeat at the Seattle Seahawks by taking on the defending champions, the New Orleans Saints. The black and gold marched over the Minnesota Vikings 14-9 in the opener last Thursday night. San Fran is a 4.5 point home underdog, making it the largest week 2 spread.

The Washington Redskins were 3.5 point underdogs last week when the Dallas Cowboys came to town, and they are once again 3.5 point pups against the other team from the Lone Star State, the Houston Texans. Houston posted arguably its biggest win in franchise history when RB Arian Foster rushed for 231 yards en route to a romp at home of the Indianapolis Colts.

The Detroit Lions probably got screwed out of what would’ve been their first road win in 22 tries against the Chicago Bears last weekend, but they will take on the Philadelphia Eagles, who could be playing without QB Kevin Kolb on Sunday. Kolb suffered a concussion last week and might be held out, especially considering how well QB Michael Vick played in his absence. The hosts are 3.5 point pups.

In the other potential marquee game on the slate in Week 2, the Minnesota Vikings are six point home favorites in QB Brett Favre’s first contest of the year in front of the hometown faithful against the Miami Dolphins.

Current 2010 NFL Football Week 2 Lines @ Oddsmaker Sportsbook (as of 9/13/10):
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Week 2 Lines For Sunday, 9/13/2010:

207 – Kansas City Chiefs OTB
208 – Cleveland Browns OTB
Over/Under OTB

209 – Buffalo Bills +13
210 -Green Bay Packers -13
Over/Under 43

211 – Baltimore Ravens OTB
212 – Cincinnati Bengals OTB
Over/Under OTB

213 – Pittsburgh Steelers +5.5
214 – Tennessee Titans -5.5
Over/Under 38

215 – Philadelphia Eagles -3.5
216 – Detroit Lions +3.5
Over/Under 41

217 – Chicago Bears +8.5
218 – Dallas Cowboys -8.5
Over/Under 41

219 – Tampa Bay Buccaneers OTB
220 – Carolina Panthers OTB
Over/Under OTB

221 – Arizona Cardinals +7
222 – Atlanta Falcons -7
Over/Under 43

223 – Miami Dolphins +6
224 – Minnesota Vikings -6
Over/Under 40

225 – St. Louis Rams +4
226 – Oakland Raiders -4
Over/Under 37.5

227 – Seattle Seahawks +3.5
228 – Denver Broncos -3.5
Over/Under 39.5

229 – Houston Texans -3.5
230 – Washington Redskins +3.5
Over/Under 44.5

231 – Jacksonville Jaguars OTB
232 – San Diego Chargers OTB
Over/Under OTB

233 – New England Patriots OTB
234 – New York Jets OTB
Over/Under OTB

235 – New York Giants +5.5
236 – Indianapolis Colts -5.5
Over/Under 47.5

Week 2 Spreads For Sunday, 9/14/2010:

237 – New Orleans Saints -4.5
238 – San Francisco 49ers +4.5
Over/Under 44