It’s not all that often that we see two teams that have both been ranked in the Top 10 in the nation that are underdogs and big ones at that at home, but that’s the case this week when we analyze the Week 10 College Football Odds.

The bigger of the two underdogs that we are referring to are the LSU Tigers. The Bayou Bengals were heavy underdogs last year going on the road against the Alabama Crimson Tide, where no one figured that they would be able to win in the battle of No. 1 against No. 2. This year, it isn’t quite the top team and the second team in the land, but there is no doubt that the stakes are huge. LSU has no choice but to win this game if it is going to be in the BCS this year, and the team hardly ever loses at home, especially at night. This is the biggest test that the seemingly unbeatable Crimson Tide will face all year long, and they are laying a whopping 10 points in their ninth, and most crucial game of the season.

Meanwhile on the other side of the country, the USC Trojans are going to be underdogs of 7.5 points at home against the Oregon Ducks. Last year, it was USC that was the underdog on the road, and it was Oregon that was expected to run away with the game. Instead, the Men of Troy were able to win the game in Autzen Stadium, a win that figured to be the rocket launcher towards a potential National Championship season. Thus far this year at home, Southern Cal hasn’t been topped, but there have already been two other Pac-12 teams, including the Arizona Wildcats last week that picked it off. It is going to take a huge effort for QB Matt Barkley to be able to win this game against one of the most exciting offenses in the nation.

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Meanwhile, there are a number of other teams that are ranked in the Top 10 in the country that are expected to be easy winners in this one. The No. 3 Kansas State Wildcats are the only other ones of the bunch that are playing against a team that is ranked in the Top 25. They are taking on the Oklahoma State Cowboys, who know all about what it is like to have the whole nation going against them in the quest for the BCS National Championship. KSU is favored by eight at home, but this is clearly a dangerous game in the murderer’s row of games that are on tap in the Big XII this year.

The fourth ranked Notre Dame Fighting Irish are in a significantly easier battle this week. They’re at home against the Pitt Panthers, who are just trying to get into a bowl game. The Golden Domers are laying 17. That’s approximately the same college football point spread that the Florida Gators are laying against the Missouri Tigers at home. Also in the SEC, the Georgia Bulldogs, fresh off of their win against Florida last week in the World’s Largest Cocktail Party, are giving two touchdowns to the Ole Miss Rebels. Winning that game would put Georgia just one step away from winning the SEC East. A loss parlayed with a Florida victory, and it will be the Gators going to the SEC Championship Game.

Other home teams that are heavy favorites in the Top 25 include the Oregon State Beavers -5.5 against the Arizona State Sun Devils, the Boise State Broncos giving 13.5 to the San Diego State Aztecs, the West Virginia Mountaineers starting seven points behind the TCU Horned Frogs, and the Temple Owls getting 14 from the Louisville Cardinals.

It’s not all fun and games for teams in the Top 25 on the Week 10 odds at home. The Stanford Cardinal and Clemson Tigers have to go on the road, but they are both heavy favorites against the Colorado Buffaloes and Duke Blue Devils respectively. There is one team that is in the Top 25, the Nebraska Cornhuskers, that are actually underdogs against an unranked team in the Michigan State Spartans. MSU really needs this one to stay in the chase for the Rose Bowl this year, and it is laying a point and a half to try to get the job done.

There are only five games this week that pit a pair of Top 25 teams against each other. We have already spoken about three of these five games, but the ones that we have yet to discuss are the Texas Tech Red Raiders hosting the Texas Longhorns and the Texas A&M Aggies against the Mississippi State Bulldogs. There could be some massive implications for the Cotton Bowl in these two games, as the winners are likely going to be on the inside track to Dallas for the postseason. Texas is going to likely be switching quarterbacks, allowing QB Case McCoy to take his shot at the Red Raiders, who haven’t won in this series since that magical win against the Horns when they were ranked No. 1 in the country four years ago. This time though, T-Tech is the 6.5-point favorite. Meanwhile, the Bulldogs are getting no respect whatsoever at home, as they are underdogs of a whopping seven points at home against Texas A&M to start the week.

The biggest favorites this week are the Northern Illinois Huskies, who are giving 35 to the Massachusetts Minutemen. There are three teams that are laying at least 31, including the Fresno State Bulldogs -33.5 against the Hawaii Warriors and the Louisiana Tech Bulldogs -31.5 against the Texas San Antonio Roadrunners.

2012 NCAA Football Week 10 Odds @ JustBet Sportsbook (as of 11/2/12):
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Week 10 College Football Betting Lines for Thursday, 11/1/12

303 Eastern Michigan Eagles +16
304 Ohio Bobcats -16
Over/Under 58.5

305 Virginia Tech Hokies -1
306 Miami Hurricanes +1
Over/Under 57.5

307 Middle Tennessee State Blue Raiders +9
308 Western Kentucky Hilltoppers -9
Over/Under 55.5

NCAA Football Lines for Week 10 for Friday, 11/2/12

309 Washington Huskies +4
310 Cal Golden Bears -4
Over/Under 50.5

Week 10 NCAA Football Odds for Saturday, 11/3/12

311 Penn State Nittany Lions -3.5
312 Purdue Boilermakers +3.5
Over/Under 51.5

313 Air Force Falcons -7
314 Army Black Knights +7
Over/Under 60.5

315 Akron Zips +20
316 Kent State Golden Flashes -20
Over/Under 59

317 Vanderbilt Commodores -7
318 Kentucky Wildcats +7
Over/Under 46

319 Massachusetts Minutemen +34.5
320 Northern Illinois Huskies -34.5
Over/Under 57

321 Temple Owls +16
322 Louisville Cardinals -16
Over/Under 50.5

323 Boston College Eagles +3
324 Wake Forest Demon Deacons -3
Over/Under 51.5

325 Houston Cougars -3.5
326 East Carolina Pirates +3.5
Over/Under 69.5

327 Iowa Hawkeyes +2.5
328 Indiana Hoosiers -2.5
Over/Under 55.5

329 Georgia Tech Yellow Jackets -8.5
330 Maryland Terrapins +8.5
Over/Under 46.5

331 Clemson Tigers -12
332 Duke Blue Devils +12
Over/Under 65.5

333 Tulsa Golden Hurricane +9
334 Arkansas Razorbacks -9
Over/Under 64.5

335 New Mexico State Aggies +22.5
336 Auburn Tigers -22.5
Over/Under 50.5

337 Stanford Cardinal -28
338 Colorado Buffaloes +28
Over/Under 51.5

339 Texas State Bobcats +26.5
340 Utah State Aggies -26.5
Over/Under 52

341 Alabama Crimson Tide -8.5
342 LSU Tigers +8.5
Over/Under 40

343 Colorado State Rams +7.5
344 Wyoming Cowboys -7.5
Over/Under 52

345 Virginia Cavaliers +10.5
346 NC State Wolfpack -10.5
Over/Under 50

347 Arizona State Sun Devils +3.5
348 Oregon State Beavers -3.5
Over/Under 56

349 Missouri Tigers +17
350 Florida Gators -17
Over/Under 41.5

351 Nebraska Cornhuskers -1.5
352 Michigan State Spartans +1.5
Over/Under 44

353 TCU Horned Frogs +4
354 West Virginia Mountaineers -4
Over/Under 69.5

355 Illinois Fighting Illini +27.5
356 Ohio State Buckeyes -27.5
Over/Under 51.5

357 Pittsburgh Panthers +17
358 Notre Dame Fighting Irish -17
Over/Under 45

359 Texas San Antonio Roadrunners +30.5
360 Louisiana Tech Bulldogs -30.5
Over/Under 73

361 San Jose State Spartans -20.5
362 Idaho Vandals +20.5
Over/Under 53

363 SMU Mustangs +9.5
364 UCF Knights -9.5
Over/Under 51

365 Connecticut Huskies +7.5
366 South Florida Bulls -7.5
Over/Under 45.5

367 Western Michigan Broncos -2
368 Eastern Michigan Eagles +2
Over/Under 61.5

369 Miami Redhawks +2.5
370 Buffalo Bulls -2.5
Over/Under 54

371 Ole Miss Rebels +14
372 Georgia Bulldogs -14
Over/Under 62

373 Syracuse Orange +4.5
374 Cincinnati Bearcats -4.5
Over/Under 57

375 Washington State Cougars +11
376 Utah Utes -11
Over/Under 49

377 UAB Blazers +3
378 Southern Miss Golden Eagles -3
Over/Under 63

379 Memphis Tigers +19.5
380 Marshall Thundering Herd -19.5
Over/Under 66

381 Michigan Wolverines -10.5
382 Minnesota Golden Gophers +10.5
Over/Under 46.5

383 Oklahoma State Cowboys +9
384 Kansas State Wildcats -9
Over/Under 66.5

385 Texas Longhorns +7
386 Texas Tech Red Raiders -7
Over/Under 67

387 Texas A&M Aggies -7
388 Mississippi State Bulldogs +7
Over/Under 60

389 Kansas Jayhawks +17
390 Baylor Bears -17
Over/Under 71

391 Oklahoma Sooners -12
392 Iowa State Cyclones +12
Over/Under 53

393 Oregon Ducks -8.5
394 USC Trojans +8.5
Over/Under 69.5

395 Rice Owls -5.5
396 Tulane Green Wave +5.5
Over/Under 63.5

397 Hawaii Warriors +33.5
398 Fresno State Bulldogs -33.5
Over/Under 60.5

399 Arizona Wildcats +3
400 UCLA Bruins -3
Over/Under 71

401 New Mexico Lobos +3.5
402 UNLV Runnin’ Rebels -3.5
Over/Under 53

403 San Diego State Aztecs +15
404 Boise State Broncos -15
Over/Under 49.5

405 Florida Atlantic Owls +15
406 Navy Midshipmen -15
Over/Under 49.5

407 Florida International Golden Panthers -3.5
408 South Alabama Jaguars +3.5
Over/Under 52

409 Troy Trojans +18
410 Tennessee Volunteers -18
Over/Under 69.5

411 Arkansas State Red Wolves -4
412 North Texas Mean Green +4
Over/Under 60

413 Louisiana Lafayette Ragin’ Cajuns +9.5
414 Louisiana Monroe Warhawks -9.5
Over/Under 62