Week 4 of the 2012 college football campaign is going to get underway this weekend. Below you will find the current list of 2012 Week 4 NCAA football lines and spreads along with a breakdown of the Week 4 college football lines. Be sure to check out the free NCAA football picks from the expert handicappers at Bankroll Sports this weekend!

We are going to have our first week of college football betting action with three weekday games before the main course kicks off on Saturday. The first of those games is in the MAC, and it pits the Buffalo Bulls against the Kent State Golden Flashes. Neither of these teams really have all that great of an offense, but neither has much of a defense either. There is a big difference between these clubs starting at 2-1 or 1-2, and one will be in each position when this one is over. This one starts the week with Buffalo at -3 on the NCAA football betting odds.

On Thursday night, the Boise State Broncos and BYU Cougars are going to battle it out in a clash of teams that want to have an impact on the BCS chase. The truth of the matter is that neither one of these teams is likely to do it, but this is certainly an elimination game for two teams that have already suffered one loss. Boise State will have the edge playing on the Smurf Turf. Both teams are coming off of a short week, but it just feels like BYU had a bit of the stuffing knocked out of it last week when it was beaten by its rivals from Utah. Boise State is laying 7.5 to open the week up.

Friday night is going to be a doozy that we are really looking forward to watching on the college football TV schedule. The Louisiana Monroe have already proven that they can play with the big boys in the SEC, and this is going to be the third straight game against a team from the AQ conferences. Baylor is right on the verge of the Top 25 once again, but this is going to be a heck of a fight, as it is the most important game in the history of the Warhawks program. Expect to see QB Nick Florence and QB Kolton Browning shooting it out in the Bayou. Baylor is getting the initial nod by 7.5-points, but it will be interesting to see what happens with this pointspread as the week goes on.

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It shouldn’t be all that much of a surprise that the number of massive, massive favorites has come down quite a bit over the course of the last few days, as there is only one team in an FBS vs. FBS game that is favored by more than 34.5 points. That title goes to the Alabama Crimson Tide, who are the No. 2 team in the nation in terms of point differential this year. Alabama is just steamrolling everyone that it runs up against, and the Florida Atlantic Owls shouldn’t be all that much of an exception. This is the first time this year that we have seen an FBS vs. FBS game feature a CFB pointspread this big though, as Alabama is laying 50 to the Sun Belt cellar dwellers.

Honorable mentions go out to the Mississippi State Bulldogs, who are -34.5 against the South Alabama Jaguars, and the Ohio State Buckeyes, who are -37.5 against the UAB Blazers.

The big time games of the weekend are all featuring point spreads that really could be dangerous for the big time teams.

We’ll start at the top of the rotation schedule with the Florida State Seminoles. They haven’t had a great history against the Clemson Tigers, and this year might not be all that much of an exception. However, what we have to note about FSU, is that this might be the only game this year in which it has to play a ranked team at the time of the game between the two teams. QB Tajh Boyd knows what it takes to beat the Noles, and Head Coach Dabo Swinney does have a win here at Doak Campbell Stadium to his credit in his career. In a game that likely could (and should) decide the winner of the ACC Atlantic Division, Florida State is -14 in primetime.

Does that 14-point spread look familiar? It’s the same number that the Oklahoma Sooners are giving to the Kansas State Wildcats. Many are thinking that this game could be an upset, though last year, with KSU still nursing an undefeated season at the time, the Sooners came to Manhattan and absolutely drubbed the Cats. Could payback be in store? QB Collin Klein and his band of purple and grey clad men are going to hope so, but as the CFB odds show, it is going to be a long, uphill climb in primetime in Norman.

The Notre Dame Fighting Irish have to think that this is the year that they can legitimately fight for the BCS National Championship. If they run the table, they’ll be hard to keep out, but they have a big time test this week against the Michigan Wolverines. The Golden Domers have already proven that they can beat the Michigan State Spartans on the road, but this is going to be a far more interesting test against a team that has such a dynamic quarterback in QB Denard Robinson. Notre Dame is laying seven, but either way, this is expected to be a heck of a close game.

The Oregon Ducks figure to be able to romp to another Pac-12 victory this week when they take on the Arizona Wildcats, but already, we have seen some major confidence in the U of A. These two teams average right at 1,200 yards per game between them, and they are sure to be squads that are ready to put some major points on the board. Oregon is starting off by laying 23.5 of them, but that line opened at 27 on Sunday afternoon and immediately dropped before the rest of the online sportsbooks opened up. This could be a game that is a lot more interesting than the college football point spread suggests.

Down in the great state of Alabama, the Tigers from Auburn will battle the Tigers from LSU in the first real test of the year for the Bayou Bengals. LSU is laying 18.5, and that’s a heck of a lot for a team to be giving on the road in a conference game with a true freshman making his first ever big time road start.

If you’re looking for some proof that some Top 10 teams from the start of the year have really fallen flat, look at the Wisconsin Badgers and Arkansas Razorbacks. They both would have been at least three touchdown favorites, and Arkansas would have probably been a five TD favorite this week at the outset of the season, but now, the Badgers are laying just 16 to the lowly UTEP Miners, while the Hogs are giving five to the Rutgers Scarlet Knights.

We also want to point out that the Minnesota Golden Gophers are one of the three teams in the Big Ten that still have spotless records this year. We know that the Buckeyes are going to improve to 4-0, but Minnesota could as well. The Gophers are laying two to the Syracuse Orange in what really might be a crucial game to the bowl hopes of both clubs.

2012 NCAA Football Week 4 Odds @ SportBet Sportsbook (as of 9/21/12):
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Week 4 College Football Betting Lines for Wednesday, 9/19/12

301 Kent State Golden Flashes +3.5
302 Buffalo Bulls -3.5
Over/Under 52

NCAA Football Lines for Week 4 for Thursday, 9/20/12

305 BYU Cougars +7.5
306 Boise State Broncos -7.5
Over/Under 48.5

College Football Point Spreads for Week 4 for Friday, 9/21/12

307 Baylor Bears -8.5
308 Louisiana Monroe Warhawks +8.5
Over/Under 70

Week 4 NCAA Football Odds for Saturday, 9/22/12

309 Army Black Knights +7
310 Wake Forest Demon Deacons -7
Over/Under 54.5

311 Clemson Tigers +14.5
312 Florida State Seminoles -14.5
Over/Under 55

313 South Florida Bulls -9
314 Ball State Falcons +9
Over/Under 58

315 Memphis Tigers +23.5
316 Duke Blue Devils -23.5
Over/Under 62.5

317 Eastern Michigan Eagles +31
318 Michigan State Spartans -31
Over/Under 49.5

319 Bowling Green Falcons +16.5
320 Virginia Tech Hokies -16.5
Over/Under 47.5

321 Central Michigan Chippewas +14.5
322 Iowa Hawkeyes -14.5
Over/Under 48.5

323 UAB Blazers +36.5
324 Ohio State Buckeyes -36.5
Over/Under 58

325 East Carolina Pirates +15
326 North Carolina Tar Heels -15
Over/Under 63

327 Temple Owls +7.5
328 Penn State Nittany Lions -7.5
Over/Under 43

329 Maryland Terrapins +26
330 West Virginia Mountaineers -26
Over/Under 59

331 UTEP Miners +18
332 Wisconsin Badgers -18
Over/Under 51

333 Massachusetts Minutemen +23.5
334 Miami Redhawks -23.5
Over/Under 49

335 Vanderbilt Commodores +14.5
336 Georgia Bulldogs -14.5
Over/Under 50

337 Utah State Aggies -12.5
338 Colorado State Rams +12.5
Over/Under 52.5

339 Rutgers Scarlet Knights +9.5
340 Arkansas Razorbacks -9.5
Over/Under 50.5

341 Fresno State Bulldogs +6.5
342 Tulsa Golden Hurricane -6.5
Over/Under 68

343 Marshall Thundering Herd -3
344 Rice Owls +3
Over/Under 70.5

345 Kansas Jayhawks +8.5
346 Northern Illinois Huskies -8.5
Over/Under 52.5

347 Arizona Wildcats +21.5
348 Oregon Ducks -21.5
Over/Under 79

349 Oregon State Beavers +7.5
350 UCLA Bruins -7.5
Over/Under 51.5

351 Virginia Cavaliers +18
352 TCU Horned Frogs -18
Over/Under 54.5

353 Cal Golden Bears +16.5
354 USC Trojans -16.5
Over/Under 58

355 Colorado Buffaloes +20
356 Washington State Cougars -20
Over/Under 58.5

357 LSU Tigers -20.5
358 Auburn Tigers +20.5
Over/Under 48.5

359 Miami Hurricanes +14
360 Georgia Tech Yellow Jackets -14
Over/Under 61.5

361 Wyoming Cowboys +2.5
362 Idaho Vandals -2.5
Over/Under 50

363 Kentucky Wildcats +23
364 Florida Gators -23
Over/Under 53

365 Connecticut Huskies +1
366 Western Michigan Broncos -1
Over/Under 41.5

367 Missouri Tigers +10.5
368 South Carolina Gamecocks -10.5
Over/Under 48

369 Michigan Wolverines +6
370 Notre Dame Fighting Irish -6
Over/Under 49.5

371 Syracuse Orange -1
372 Minnesota Golden Gophers +1
Over/Under 54

373 Kansas State Wildcats +16.5
374 Oklahoma Sooners -16.5
Over/Under 56.5

375 New Mexico Lobos +6
376 New Mexico State Aggies -6
Over/Under 55.5

377 Akron Zips +33
378 Tennessee Volunteers -33
Over/Under 65

379 Ole Miss Rebels -19
380 Tulane Green Wave +19
Over/Under 54.5

381 Louisiana Tech Bulldogs +3
382 Illinois Fighting Illini -3
Over/Under 62.5

383 Utah Utes +6
384 Arizona State Sun Devils -6
Over/Under 50

385 San Jose State Spartans +2.5
386 San Diego State Aztecs -2.5
Over/Under 53

387 Air Force Falcons -10.5
388 UNLV Runnin’ Rebels +10.5
Over/Under 55

389 Nevada Wolf Pack -7
390 Hawaii Warriors +7
Over/Under 62.5

391 Florida Atlantic Owls +48.5
392 Alabama Crimson Tide -48.5
Over/Under 58

393 Southern Mississippi Golden Eagles +3.5
394 Western Kentucky Hilltoppers -3.5
Over/Under 48

395 Troy Trojans -2
396 North Texas Mean Green +2
Over/Under 62

397 Louisville Cardinals -13.5
398 Florida International Golden Panthers -13.5
Over/Under 53.5

399 South Alabama Jaguars +34
400 Mississippi State Bulldogs -34
Over/Under 49

441 South Dakota Coyotes +29.5
442 Northwestern Wildcats -29.5

443 Norfolk State Spartans +29
444 Ohio Bobcats -29

445 South Carolina State Bulldogs +51
446 Texas A&M Aggies -51

447 Idaho State Bengals +46
448 Nebraska Cornhuskers -46

449 Stephen F. Austin Lumberjacks +4.5
450 Texas State Bobcats -4.5

451 VMI Keydets +40.5
452 Navy Midshipmen -40.5

453 Gardner Webb Bulldogs +46
454 Pittsburgh Panthers -46

455 The Citadel Bulldogs +14
456 North Carolina State Wolfpack -14

457 Alcorn State Braves +46
458 Arkansas State Red Wolves -46

459 Coastal Carolina Chanticleers +31.5
460 Toledo Rockets -31.5