One week of NFL betting action is in the books, and here at Bankroll Sports, we are set to give it a go with our Week 2 NFL betting lines. Join us as we break down all 16 of the games on the NFL rotation schedule and check out which ones have the hottest bets to place.

For the second straight weekend, the New England Patriots are going to be the biggest favorites on the NFL odds, and we still aren’t all that sure that they are that good. This time, they’ve got the New York Jets coming to town for the home opener in Foxboro, but we still see a heck of a lot of problems. RB Stevan Ridley is fumbling the ball all over the place, while RB Shane Vereen is now going to join TE Rob Gronkowski on the sidelines injured. The receivers don’t really look like they have much of a clue as to where they are running routes to on a regular basis, and that’s going to prove to be problematic going forward. QB Geno Smith won the first start of his career against the Bucs, but this is a much, much different task going on the road to Foxboro on a short week of preparation against the behemoths of the division.

Last week, we had a ton of very close NFL point spreads, but this week, the numbers are a lot more spread out. There are eight spreads that are featuring at least 6.5 points or more, and a lot of those games wouldn’t have been set this high even just a week ago.

For example, on Monday Night Football, the Cincinnati Bengals are taking on the Pittsburgh Steelers. Just last week before any game kicked off, the Bengals were slated to be -1.5 in that game. Now, after Pittsburgh looked so horrid in its opener against the Titans, it has risen all the way up to +6.5. Of course, injuries have a lot to do with that, knowing that the Steelers lost three players, most notably OL Maurkice Pouncey to season ending injuries on Sunday as well. The bottom line for Pittsburgh though, is that it cannot run the football to save its life for the second straight season, and regardless of who is back there, we don’t see any improvement. About the only good news for Pittsburgh is that everyone lost in Week 1 in the AFC North, and the possibility is there to rebound. Still, QB Andy Dalton looks the better of the two quarterbacks in this game at this point, and it is very justifiable to think that the Bengals could open at -6.5.

Other teams that are favored by 6.5 on Sunday include the Chicago Bears over the Minnesota Vikings, the Green Bay Packers over the Washington Redskins, the Baltimore Ravens over the Cleveland Browns, and perhaps most interesting of them all, the Philadelphia Eagles over the San Diego Chargers. There was a lot of respect here for the Chargers after a half of football against the Texans on Monday, but in the end, they were demoralized, getting beaten 31-28 after giving up 24 unanswered points to end the game. Philly meanwhile, has seen its stock shoot upward immediately. The Eagles were slight underdogs against the Redskins last week, and they turned out a tremendous performance, including running 53 plays in the first half, the most in an NFL game in the first half since the 1998 Vikings ran 58 plays in the first half. Head Coach Chip Kelly and company are amongst the big time movers and shakers, and there is a great chance that they could start at 2-0 this year. Do keep in mind though, that San Diego is 7-0 ATS in its last seven games played on short rest, and coming off of a Monday Night Football game into a Sunday game across the country, the Bolts are sure to be sharp as could be.

There are a couple other teams that are favored by more than 6.5. The Houston Texans, fresh off of their comeback we just spoke of against San Diego, will look to tame the Tennesssee Titans in their home opener as 8.5-point favorites on the NFL lines, while the Atlanta Falcons are giving seven to the St. Louis Rams.

There are going to be some tremendous close calls as well. The Carolina Panthers and New Orleans Saints are both AFC South teams that are favored by three on the road. The Panthers head north to take on the Buffalo Bills in a battle of 0-1 teams that lost heartbreakers against superior squads last week. New Orleans has the Tampa Bay Buccaneers in a second straight crucial NFC South battle.

It’s amazing how quickly some are selling on the Indianapolis Colts. The team was favored by double digits last week and steamed like crazy against Oakland, yet now, it is only favored by three, the value of their home field advantage against the Miami Dolphins. QB Andrew Luck and company could be in for an upset if the oddsmakers have pegged this one even remotely right. Meanwhile, the Kansas City Chiefs are trending upward after crushing the Jags on Sunday, as they are favored by a field goal in their home opener against the Dallas Cowboys.

In the late games, the Detroit Lions and Arizona Cardinals are lined at a pick ’em, while the Oakland Raiders are 5.5-point favorites over the Jacksonville Jaguars. The last time Oakland was favored by more than four points was against none other than these Jaguars last year at the O.co Coliseum.

But of course, we still have yet to talk about the two biggest games of the weekend. The national game in the 4:00 ET hour is the clash of the Manning brothers. Younger brother QB Eli Manning had a rough go of it against the Cowboys last week, but he is still set to lead his New York Giants into battle against QB Peyton Manning and his Denver Broncos. The elder Manning threw an NFL record seven touchdown passes against Baltimore on Thursday last week, and he has a long week to prepare for his trip to the Meadowlands. If New York loses this game and starts at 0-2, the buzzards are going to start to swarm around Head Coach Tom Coughlin once again.

But the biggest game is the one in the NFC West between the Seattle Seahawks and the San Francisco 49ers. Neither of these two played quite as well as perhaps their fans had been hoping for in Week 1, but both escaped with narrow victories to move to 1-0. This one though, is going to be a flat out war. Seattle hasn’t lost a game at home in darn near two full calendar years, and the 49ers were absolutely destroyed last season when they went to CenturyLink Field. The winner is probably going to hold the upper hand on the loser for at least the first part of the season until the return matchup at Candlestick Park later on this season. QB Russell Wilson and QB Colin Kaepernick should both be in for stern tests. The slight edge goes to Seattle at -2.5, but no results will be surprising.

Regarding ‘totals’ this week, the Manning Bowl features the highest number on the board at 54.5, and that shouldn’t be all that surprising that the number is that high. Last week featured 64 touchdown passes in the 16 games combined, the most in a single week in NFL history. Not surprisingly, there is only one game with a ‘total’ in the 30s, and that’s the clash between the offensively inept Jags and the offensive-sporadic Raiders, a number which is set at 39.5. The Monday nighter in the AFC North only sees a ‘total’ of 40.5 hit the NFL rotation schedule, while there are five other games in which a ‘total’ of at least 47 opened on the board. If you’re looking for some big time line movement on a ‘total’, consider the game between the Chargers and the Eagles. Both teams played high scoring Monday Night Football games last week, and Philly is going to be a trendy ‘over’ team all year long until Head Coach Chip Kelly and his mates slow down just a bit, something that we don’t see happening any time in the near future.
2013 NFL Week 2 Lines @ WagerWeb Sportsbook (as of 9/14/13):
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Week 2 NFL Pointspreads for Thursday, September 12th
101 New York Jets +12
102 New England Patriots -12
Over/Under 43

Week 2 NFL Spreads for Sunday, September 15th (1:00 ET Kickoffs)
195 San Diego Chargers +7
196 Philadelphia Eagles -7
Over/Under 54.5

197 Cleveland Browns +6.5
198 Baltimore Ravens -6.5
Over/Under 43.5

199 Tennessee Titans +9.5
200 Houston Texans -9.5
Over/Under 43

201 Miami Dolphins +2.5
202 Indianapolis Colts -2.5
Over/Under 43.5

203 Carolina Panthers -3
204 Buffalo Bills +3
Over/Under 43

205 St. Louis Rams +6.5
206 Atlanta Falcons -6.5
Over/Under 46.5

207 Washington Redskins +7
208 Green Bay Packers -7
Over/Under 49.5

209 Dallas Cowboys +3
210 Kansas City Chiefs -3
Over/Under 46.5

211 Minnesota Vikings +5.5
212 Chicago Bears -5.5
Over/Under 41.5

NFL Week 2 Lines for Sunday, September 15th (4:00 ET Kickoffs)
213 New Orleans Saints -3
214 Tampa Bay Buccaneers +3
Over/Under 47

215 Detroit Lions -2
216 Arizona Cardinals +2
Over/Under 48

217 Jacksonville Jaguars +5.5
218 Oakland Raiders -5.5
Over/Under 40

219 Denver Broncos -4
220 New York Giants +4
Over/Under 54.5

Week 2 Sunday Night Football Lines for Sunday, September 15th
221 San Francisco 49ers +2.5
222 Seattle Seahawks -2.5
Over/Under 44.5

Week 2 Monday Night Football Lines for Monday, September 16th
223 Pittsburgh Steelers +7
224 Cincinnati Bengals -7
Over/Under 40.5